Sequencing and analysis of the complete mitochondrial genome of dog roundworm Toxocara canis (Nematoda: Toxocaridae) from USA

Xiaduo Meng; Yue Xie; Xiaobin Gu; Youle Zheng; Yunjian Liu; Yingxin Li; Lu Wang; Xuan Zhou; Zhicai Zuo; Guangyou Yang

doi:10.1080/23802359.2019.1666042

Sequencing and analysis of the complete mitochondrial genome of dog roundworm Toxocara canis (Nematoda: Toxocaridae) from USA

Mitochondrial DNA B Resour. 2019 Sep 13;4(2):2999-3001. doi: 10.1080/23802359.2019.1666042.

Authors

Xiaduo Meng¹, Yue Xie¹, Xiaobin Gu¹, Youle Zheng¹, Yunjian Liu¹, Yingxin Li¹, Lu Wang¹, Xuan Zhou², Zhicai Zuo³, Guangyou Yang¹

Affiliations

¹ Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
² Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
³ Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.

Abstract

The dog roundworm Toxocara canis (Nematoda: Toxocaridae) is an important zoonotic parasitic nematode and cause toxocariasis in human with a worldwide distribution. Herein, the complete mitochondrial genome of a representative of this nematode from USA was determined through next generation sequencing platform. The whole genome was 14,309 bp in size and encoded 12 protein-coding genes, 22 transfer RNAs, and 2 ribosomal RNAs. Phylogeny showed that although T. canis from USA and Australia were more closely related to each other than to that from Chinese, three T. canis isolates clustered together and formed paraphyletic relationships with T. cati and T. malayensis, supporting them as sister species among the family Toxocaridae. These cumulative mitochondrial DNA data should contribute to a better understanding of the phylogenetic relationship of this species.

Keywords: Toxocara canis; mitochondrial genome; phylogeny; toxocariasis.