Larvicidal composite alginate hydrogel combined with a Pickering emulsion of essential oil

Jonghyun Shin; Seon-Mi Seo; Il-Kwon Park; Jinho Hyun

doi:10.1016/j.carbpol.2020.117381

Larvicidal composite alginate hydrogel combined with a Pickering emulsion of essential oil

Carbohydr Polym. 2021 Feb 15:254:117381. doi: 10.1016/j.carbpol.2020.117381. Epub 2020 Nov 21.

Authors

Jonghyun Shin¹, Seon-Mi Seo², Il-Kwon Park², Jinho Hyun³

Affiliations

¹ Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea; Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul, 08826, Republic of Korea.
² Department of Forestry Sciences, Seoul National University, Seoul 08826, Republic of Korea; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea; Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul, 08826, Republic of Korea.
³ Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: jhyun@snu.ac.kr.

PMID: 33357888
DOI: 10.1016/j.carbpol.2020.117381

Abstract

Sulfonated cellulose nanocrystals (S-CNCs) can be used to encapsulate thyme white essential oil (EO) that is volatile and immiscible with water. S-CNCs form a Pickering emulsion (PE) with EOs and the micron-scale PEs are embedded in sodium alginate (SA) to form macroscale hydrogel beads. The incorporation of PEs with SA is confirmed with FTIR, XRD, SEM and confocal microscopic characterizations and the release behavior is monitored to understand the time-dependent biological activity of the EOs. The larvicidal performance of the SA-PE composite hydrogel beads is investigated with Aedes albopictus (Skuse) larvae. The larvicidal activity is higher for SA/PE hydrogel beads prepared at 0.5 % CaCl₂ than 0.75 or 1.0 % CaCl₂ due to their higher release rate.

Keywords: Cellulose nanocrystal; Essential oil; Larvicidal activity; Pickering emulsion; Sodium alginate.

MeSH terms

Aedes / physiology*
Alginates / chemistry*
Animals
Cellulose / chemistry
Drug Compounding / methods
Emulsions / chemistry*
Hydrogels / chemistry*
Larva / drug effects*
Nanoparticles / chemistry
Oils, Volatile / chemistry*
Oils, Volatile / pharmacology*
Thymus Plant / chemistry*
Volatilization
Water / chemistry

Substances

Alginates
Emulsions
Hydrogels
Oils, Volatile
Water
Cellulose