Detection and estimating the blood accumulation volume of brain hemorrhage in a human anatomical skull using a RF single coil

Moshe Oziel; Boris Rubinsky; Rafi Korenstein

doi:10.7717/peerj.10416

Detection and estimating the blood accumulation volume of brain hemorrhage in a human anatomical skull using a RF single coil

PeerJ. 2020 Dec 10:8:e10416. doi: 10.7717/peerj.10416. eCollection 2020.

Authors

Moshe Oziel¹, Boris Rubinsky², Rafi Korenstein¹

Affiliations

¹ Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv, Israel.
² Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.

Abstract

Objective: An experimental study for testing a simple robust algorithm on data derived from an electromagnetic radiation device that can detect small changes in the tissue/fluid ratio in a realistic head configuration.

Methods: Changes in the scattering parameters (S₂₁) of an inductive coil resulting from injections of chicken blood in the 0-18 ml range into calf brain tissue in a human anatomical skull were measured over a 100-1,000 MHz frequency range.

Results: An algorithm that combines amplitude and phase results was found to detect changes in the tissue/fluid ratio with 90% accuracy. An algorithm that estimated the injected blood volume was found to have a 1-4 ml average error. This demonstrates the possibility of the inductive coil-based device to possess a practical ability to detect a change in the tissue/fluid ratio in the head.

Significance: This study is an important step towards the goal of building an inexpensive and safe device that can detect an early brain hemorrhagic stroke.

Keywords: Hematoma; Inductive coil; Monitoring; Non-contact; Radiofrequency.

Grants and funding

The authors received no funding for this work.