Histological findings in skeletal muscle of SARS-CoV2 infected patient

J Immunoassay Immunochem. 2020 Nov 1;41(6):1000-1009. doi: 10.1080/15321819.2020.1863819. Epub 2020 Dec 22.

Abstract

Autopsies represent medical procedures through which the causes of patients' deaths are determined or, through tissue sampling and microscopic examination of slides in usual stains or special tests, one can offer the basis for understanding the physiopathological mechanisms that contribute to the patients' death Histological findings of tissue samples from patients who have died of COVID-19 have been mainly orientated to lung, heart, liver, kidney damage with a small percent of them following other organs, but none has, to our knowledge, studied skeletal muscle.

Keywords: Autopsy; COVID-19; skeletal muscle.

Publication types

  • Case Reports

MeSH terms

  • Autopsy
  • COVID-19 / pathology*
  • Creatine Kinase / blood
  • Endothelium, Vascular / pathology
  • Fatal Outcome
  • Humans
  • Inflammation
  • Ischemia / pathology
  • Kidney Tubules / pathology
  • Male
  • Middle Aged
  • Muscle, Skeletal / immunology
  • Muscle, Skeletal / pathology*
  • Muscle, Skeletal / virology*
  • Necrosis*
  • Tissue Distribution

Substances

  • Creatine Kinase