Gold nanoparticles modified graphene platforms for highly sensitive electrochemical detection of vitamin C in infant food and formulae

Food Chem. 2021 May 15:344:128692. doi: 10.1016/j.foodchem.2020.128692. Epub 2020 Nov 23.

Abstract

An easy and reliable method based on a novel electroanalytical nanostructured sensor has been developed to perform quantification of vitamin C in commercial and fortified cow-milk-based formulae and foods for infants and young children. The work is motivated by the need of a reliable analytical tool to be applied in quality control laboratories for the quantitative assessment of vitamin C where its rapid and cost-effective monitoring is essential. The ad hoc designed sensor, based on disposable screen-printed carbon electrodes modified with Au nanoparticles decorated reduced graphene oxide flakes, exhibits a LOD of 0.088 mg L-1. The low cost, easy sample preparation, fast response and high reproducibility (RSD ≈ 8%) of the proposed method highlight its suitability for usage in quality control laboratories for determining vitamin C in real complex food matrices, envisaging the application of the sensing platform in the determination of other compounds relevant in food chemistry and food manufacturing.

Keywords: Ascorbic acid; Colloidal Au nanoparticles; Commercial fortified food and formulae; Electrochemical sensor; Quality control; Reduced graphene oxide; Screening; Vitamin C.

MeSH terms

  • Animals
  • Ascorbic Acid / analysis*
  • Electrochemical Techniques / methods*
  • Electrodes
  • Food, Fortified / analysis
  • Gold / chemistry*
  • Graphite / chemistry*
  • Humans
  • Infant
  • Infant Food / analysis*
  • Limit of Detection
  • Metal Nanoparticles / chemistry*
  • Milk / chemistry
  • Reproducibility of Results

Substances

  • graphene oxide
  • Gold
  • Graphite
  • Ascorbic Acid