A Potential Bioelectromagnetic Method to Slow Down the Progression and Prevent the Development of Ultimate Pulmonary Fibrosis by COVID-19

Front Immunol. 2020 Dec 4:11:556335. doi: 10.3389/fimmu.2020.556335. eCollection 2020.

Abstract

Introduction: Right now, we are facing a global pandemic caused by the coronavirus SARS-CoV-2 that causes the highly contagious human disease COVID-19. The number of COVID-19 cases is increasing at an alarming rate, more and more people suffer from it, and the death toll is on the rise since December 2019, when COVID-19 has presumably appeared. We need an urgent solution for the prevention, treatment, and recovery of the involved patients.

Methods: Modulated electro-hyperthermia (mEHT) is known as an immuno-supportive therapy in oncology. Our proposal is to apply this method to prevent the progression of the disease after its identification, to provide treatment when necessary, and deliver rehabilitation to diminish the fibrotic-often fatal-consequences of the infection.

Hypothesis: The effects of mEHT, which are proven for oncological applications, could be utilized for the inactivation of the virus or for treating the fibrotic consequences. The hypothesized mEHT effects, which could have a role in the antiviral treatment, it could be applied for viral-specific immune-activation and for anti-fibrotic treatments.

Keywords: SARS-CoV-21; electric field; heat-shock protein; immune-effect; modulated electro-hyperthermia; rehabilitation.

Publication types

  • Review

MeSH terms

  • COVID-19 / complications
  • COVID-19 / epidemiology
  • COVID-19 / rehabilitation*
  • Electric Stimulation Therapy*
  • Humans
  • Hyperthermia, Induced*
  • Immunotherapy*
  • Pulmonary Fibrosis / epidemiology
  • Pulmonary Fibrosis / etiology
  • Pulmonary Fibrosis / rehabilitation*
  • SARS-CoV-2*