Risk and Predictive Factors for Proximal Junctional Kyphosis in Patients Treated by Lenke Type 5 Adolescent Idiopathic Scoliosis Correction

World Neurosurg. 2021 Mar:147:e315-e323. doi: 10.1016/j.wneu.2020.12.044. Epub 2020 Dec 15.

Abstract

Objective: Proximal junctional kyphosis (PJK) is a common sagittal complication of adolescent idiopathic scoliosis (AIS) after corrective surgery, leading to new deformities, pain, and, even, revision surgery. In the present study, we investigated the risk and predictive factors for PJK in patients who had undergone Lenke type 5 AIS correction to identify the parameters relevant to intraoperative guidance.

Methods: A total of 35 patients with Lenke type 5 AIS who had undergone corrective surgery at our hospital from January 2008 to February 2016 were divided into the PJK (n = 15) and non-PJK (n = 20) groups. Correlation and receiver operating characteristic curve analyses were performed to screen the parameters for significance and calculate the thresholds. A survival analysis was performed to examine the differences between the 2 groups.

Results: Independent t tests revealed significant differences between the 2 groups in the preoperative pelvic incidence, preoperative pelvic tilt, postoperative proximal junctional angle (PJA), and postoperative thoracic kyphosis (TK). The postoperative PJA, postoperative TK, and other parameters correlated significantly with changes in the PJA at the final follow-up. The receiver operating characteristic curves revealed that the postoperative PJA and postoperative TK effectively predicted for the occurrence of PJK, with a threshold of 9.45° and 25.25°, respectively. The estimated survival times were 14.7 months for a PJA >9.45° and TK >25.25°, 19.2 months for a PJA >9.45°, and 33.9 months for TK >25.25°.

Conclusions: The results of the present study have shown that the postoperative PJA and postoperative TK can be used to effectively predict for the occurrence of PJK in patients with Lenke type 5 AIS after corrective surgery, with a threshold of 9.45° and 25.25°, respectively.

Keywords: Adolescent idiopathic scoliosis; Lenke type 5; Predictor; Proximal junctional kyphosis; Risk factor.

MeSH terms

  • Adolescent
  • Child
  • Female
  • Humans
  • Incidence
  • Kyphosis / epidemiology*
  • Kyphosis / surgery*
  • Male
  • Musculoskeletal Abnormalities / surgery
  • Postoperative Complications / etiology*
  • Postoperative Complications / surgery
  • Postoperative Period
  • Reoperation / methods
  • Retrospective Studies
  • Risk Factors
  • Scoliosis / surgery*
  • Spinal Fusion / adverse effects