Functional foods from the tropics to relieve chronic normobaric hypoxia

Abstract

Functional foods with antioxidant and anti-inflammatory properties are regarded as a complementary therapy to improve chronic diseases such as obesity and inflammatory bowel disease (IBD). Obesity is a chronic low-grade inflammatory state leading to organ damage with increased risk of common diseases including cardiovascular and metabolic disease, non-alcoholic fatty liver disease, osteoarthritis and some cancers. IBD is a chronic intestinal inflammation categorised as Crohn's disease and ulcerative colitis depending on the location of inflammation. These inflammatory states are characterised by normobaric hypoxia in adipose and intestinal tissues, respectively. Tropical foods especially from Australia and South America are discussed in this review to show their potential in attenuation of these chronic diseases. The phytochemicals from these foods have antioxidant and anti-inflammatory activities to reduce chronic normobaric hypoxia in the tissues. These health benefits of the tropical foods are relevant not only for health economy but also in providing a global solution by improving the sustainability of their cultivation and assisting the local economies.

Keywords: Chronic hypoxia; Inflammatory bowel disease; Obesity; Tropical foods.