Improved visuospatial neglect after tDCS and computer-assisted cognitive training in Posterior Cortical Atrophy: a single-case study

Neurocase. 2021 Feb;27(1):57-63. doi: 10.1080/13554794.2020.1862242. Epub 2020 Dec 17.

Abstract

Visuospatial neglect (VN) frequently occurs in Posterior Cortical Atrophy (PCA) and requires specific rehabilitation. In this single-case study, we investigated the efficacy of a computer-assisted cognitive training (CCT) alone or coupled with multiple sessions of anodal transcranial direct-current stimulation (A-tDCS) over the right posterior parietal cortex in improving left VN symptoms in a patient with PCA. The digital ReMoVES platform was used for both VN assessment and training. We found a significant improvement after CCT combined with A-tDCS within the limits of a single-case, our results suggest, for the first time, the usefulness of this combined approach in a neurodegenerative disorder.

Keywords: Visuospatial neglect; computer-assisted cognitive training; posterior cortical atrophy; posterior parietal cortex; tDCS.

MeSH terms

  • Atrophy
  • Cognition
  • Computers
  • Humans
  • Neurodegenerative Diseases* / complications
  • Neurodegenerative Diseases* / therapy
  • Transcranial Direct Current Stimulation*