Discovery of Lanama Virus, a Distinct Member of Species Kunsagivirus C (Picornavirales: Picornaviridae), in Wild Vervet Monkeys (Chlorocebus pygerythrus)

Jens H Kuhn; Samuel D Sibley; Colin A Chapman; Nick J Knowles; Michael Lauck; Joshua C Johnson; Cristine Campos Lawson; Matthew G Lackemeyer; Kim Valenta; Patrick Omeja; Peter B Jahrling; David H O'Connor; Tony L Goldberg

doi:10.3390/v12121436

Discovery of Lanama Virus, a Distinct Member of Species Kunsagivirus C (Picornavirales: Picornaviridae), in Wild Vervet Monkeys (Chlorocebus pygerythrus)

Viruses. 2020 Dec 14;12(12):1436. doi: 10.3390/v12121436.

Authors

Affiliations

¹ Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD 21702, USA.
² Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.
³ Department of Anthropology, Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC 20052, USA.
⁴ School of Life Sciences, Pietermaritzburg Campus, University of KwaZulu-Natal, Scottsville 3209, South Africa.
⁵ Shaanxi Key Laboratory for Animal Conservation, School of Life Sciences, Northwest University, Xi'an 710069, China.
⁶ Makerere University Biological Field Station, P.O. Box 409, Fort Portal, Uganda.
⁷ The Pirbright Institute, Pirbright, Woking, Surrey GU24 0NF, UK.
⁸ Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA.
⁹ Department of Anthropology, University of Florida, Gainesville, FL 32603, USA.
¹⁰ Wisconsin National Primate Research Center, Madison, WI 53715, USA.

Abstract

We report the discovery and sequence-based molecular characterization of a novel virus, lanama virus (LNMV), in blood samples obtained from two wild vervet monkeys (Chlorocebus pygerythrus), sampled near Lake Nabugabo, Masaka District, Uganda. Sequencing of the complete viral genomes and subsequent phylogenetic analysis identified LNMV as a distinct member of species Kunsagivirus C, in the undercharacterized picornavirid genus Kunsagivirus.

Keywords: Chlorocebus pygerythrus; LNMV; Picornavirales; Picornaviridae; kunsagivirus; lanama virus; nonhuman primate; vervet.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Chlorocebus aethiops / virology*
Genome, Viral
Genomics / methods
High-Throughput Nucleotide Sequencing
Monkey Diseases / virology*
Phylogeny
Picornaviridae / classification*
Picornaviridae Infections / veterinary*

Abstract

Publication types

MeSH terms

Grants and funding