The intestinal barrier, an arbitrator turned provocateur in IBD

Nat Rev Gastroenterol Hepatol. 2021 Feb;18(2):83-84. doi: 10.1038/s41575-020-00399-w.

Authors

Saurabh Mehandru^{1

2}, Jean-Frederic Colombel³

Affiliations

¹ Department of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
² Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
³ Department of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. jean-frederic.colombel@mssm.edu.

PMID: 33318680
DOI: 10.1038/s41575-020-00399-w

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antibodies, Bacterial / immunology
Antibodies, Fungal / immunology
Colon / immunology
Colon / metabolism*
Crohn Disease / immunology
Crohn Disease / metabolism*
Diet
Enterocytes / metabolism
Gastrointestinal Microbiome*
Histocompatibility Antigens Class II / immunology
Humans
Inflammatory Bowel Diseases / immunology
Inflammatory Bowel Diseases / metabolism
Interleukin-10 / immunology
Intestinal Absorption
Intestinal Mucosa / immunology
Intestinal Mucosa / metabolism*
Intestine, Small / immunology
Intestine, Small / metabolism*
Intraepithelial Lymphocytes / immunology
Macrophages
Mice
Mycotoxins / metabolism
Permeability*
Prodromal Symptoms

Substances

Antibodies, Bacterial
Antibodies, Fungal
Histocompatibility Antigens Class II
Mycotoxins
Interleukin-10