Mesenteric ischemia (MI) is a rare medical condition which involves insufficient blood supply, inflammatory injury and eventually bowel wall necrosis with high mortality rates. Acute mesenteric ischemia (AMI) and chronic mesenteric ischemia (CMI) are the two major types of mesenteric ischemia. Therapeutic approach of MI includes medical as well as surgical treatment. This review article aims to delineate the abreast knowledge on indications, management through mesenteric bypass surgical technique, and clinical outcomes. Clinical presentation of AMI and CMI varies substantially, depending on the etiology underlying it. The most common symptom of AMI is abdominal pain that is disproportionate to the outcomes of physical exams; whereas CMI normally induces postprandial abdominal pain, commonly epigastric or periumbilical, nausea and weight loss. Recent awareness of AMI management revealed that exploratory laparotomy surgical procedure with careful evaluation of bowel viability played a pivotal role in restoring intestinal oxygenation and avoiding serious complications such as peritonitis and perforation of the gangrene bowels. The management of CMI is mainly surgical, with Aorta/Iliac-SMA bypass and Aorta-Splenic bypass being the currently available options. Due to the high thrombosis levels, only patients whose surgical risk outweighs possible benefits are required for medical care as a single treatment. Furthermore, this review also postulates that aorto mesenteric revascularization procedures for chronic mesenteric ischemia are feasible, but involve careful selection of patients, and they should only be performed by vascular surgeons with extensive experience in laparoscopic vascular surgery at referral centers.