Prevalence of antimicrobial use in a tertiary academic hospital: a venue for antimicrobial stewardship programs

Expert Rev Anti Infect Ther. 2021 Aug;19(8):1047-1051. doi: 10.1080/14787210.2021.1863789. Epub 2020 Dec 21.

Abstract

Objective: To quantify antimicrobial use in inpatients setting as part of antimicrobial stewardship program surveillance.

Method: Antimicrobial use was obtained using a pre-designed data collection form in this point prevalence study. Setting: The study was conducted in a tertiary academic hospital in the North of Jordan on 13 August 2018. Main outcome measures: antimicrobial use was determined using two methods: defined daily use (DDD) and days of therapy (DOT).

Results: This study identified antimicrobial use in 144 patients. Carbapenems, glycopeptides, and piperacillin-tazobactam were the most utilized antimicrobials in the inpatients' setting in both measures DDD and DOT. The highest prescription rate of antibiotics was in the internal medicine wards (49.8 DDD/100 admissions), followed by surgery wards (33.2 DDD/100 admissions) and intensive care unit (20.6 DDD/100 admissions).

Conclusion: This surveillance study addressed patterns of antimicrobial usage in inpatients settings in a tertiary care hospital in Jordan. This practice is feasible and could be adopted routinely by antimicrobial stewardship programs.

Keywords: Antimicrobial tracking; DDD; DOT; antimicrobial stewardship; point prevalence.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Infective Agents / administration & dosage*
  • Antimicrobial Stewardship*
  • Child
  • Cross-Sectional Studies
  • Female
  • Humans
  • Intensive Care Units / statistics & numerical data
  • Jordan
  • Male
  • Middle Aged
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Prevalence
  • Tertiary Care Centers
  • Young Adult

Substances

  • Anti-Infective Agents