Flaxseed oil stimulates gynecomastia

BMJ Case Rep. 2020 Dec 10;13(12):e237948. doi: 10.1136/bcr-2020-237948.

Abstract

Flaxseed oil contains lignans, which exhibit anti-inflammatory and antiatherogenic activities. A 70-year-old male patient presented to our office due to hyperlipidaemia and started to take a tablespoon of flaxseed oil daily. Three months later, he reported left breast swelling and pain. Although the echogram revealed a tumour in the left mammary gland, the breast biopsy was compatible with gynecomastia, showing ductal hyperplasia without evidence of malignancy. His breast epithelia were oestrogen receptor-positive. Potential role of phytoestrogens was discussed.

Keywords: endocrine system; lipid disorders; oncology.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Gynecomastia / chemically induced*
  • Gynecomastia / pathology
  • Humans
  • Hyperlipidemias / drug therapy
  • Lignans / adverse effects*
  • Linseed Oil / chemistry*
  • Male
  • Phytoestrogens / adverse effects*

Substances

  • Lignans
  • Phytoestrogens
  • Linseed Oil