Skin and Soft Tissue Infections in Patients with Diabetes Mellitus

Infect Dis Clin North Am. 2021 Mar;35(1):183-197. doi: 10.1016/j.idc.2020.10.007. Epub 2020 Dec 7.

Abstract

Skin and soft tissue infections are common in diabetics. Diabetic foot infection usually results from disruption of the skin barrier, trauma, pressure, or ischemic wounds. These wounds may become secondarily infected or lead to development of adjacent soft tissue or deeper bone infection. Clinical assessment and diagnosis of these conditions using a multidisciplinary management approach, including careful attention to antibiotic selection, lead to the best outcomes in patient care.

Keywords: Charcot; Diabetic; Foot; Infection; Wound.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Debridement / methods
  • Diabetes Mellitus / epidemiology*
  • Diabetes Mellitus / therapy
  • Diabetic Foot / epidemiology
  • Diabetic Foot / therapy
  • Drug Resistance, Bacterial
  • Gangrene / epidemiology
  • Humans
  • Osteomyelitis / epidemiology
  • Skin Diseases, Infectious / diagnosis
  • Skin Diseases, Infectious / epidemiology*
  • Skin Diseases, Infectious / therapy
  • Soft Tissue Infections / diagnosis
  • Soft Tissue Infections / epidemiology*
  • Soft Tissue Infections / therapy

Substances

  • Anti-Bacterial Agents