Corneal and Conjunctival Calcification in a Dialysis Patient Reversed by Parathyroidectomy

Blood Purif. 2021;50(2):254-256. doi: 10.1159/000508804. Epub 2020 Dec 10.

Abstract

Mineral and bone metabolism disorders are relatively common among patients with end-stage renal disease on maintenance hemodialysis. Corneal and conjunctival calcification is the main extravascular site for calcification. Recently, this form of calcification has been linked to vascular calcification. Secondary hyperparathyroidism can lead to high levels of calcium and phosphorus and increase the risk of calcification. Here, we report a case of a 38-year-old female with severe hyperparathyroidism who underwent eye examination before and after parathyroidectomy. Anterior segment optical coherence tomography showed an improvement in the number and size of ocular calcifications 6 months after surgery. This case calls attention to the importance of eye examination in patients on dialysis and brings the possibility of recovery of calcification in a short-term follow-up.

Keywords: Chronic kidney disease; Eye calcification; Hemodialysis; Hyperparathyroidism; Tomography of optical coherence.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Calcinosis / pathology
  • Calcinosis / therapy*
  • Conjunctiva / pathology*
  • Cornea / pathology*
  • Female
  • Humans
  • Hyperparathyroidism, Secondary / complications*
  • Hyperparathyroidism, Secondary / pathology
  • Hyperparathyroidism, Secondary / therapy
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / pathology
  • Kidney Failure, Chronic / therapy
  • Parathyroidectomy*
  • Renal Dialysis