Association Between Physical Activity and Schizophrenia: Results of a 2-Sample Mendelian Randomization Analysis

JAMA Psychiatry. 2021 Apr 1;78(4):441-444. doi: 10.1001/jamapsychiatry.2020.3946.

Authors

Sergi Papiol^{1

2}, Andrea Schmitt^{1

3}, Isabel Maurus¹, Moritz J Rossner¹, Thomas G Schulze^{2

4}, Peter Falkai¹

Affiliations

¹ Department of Psychiatry, University Hospital, Munich, Germany.
² Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University, Munich, Germany.
³ Laboratory of Neuroscience, Institute of Psychiatry, University of Sao Paulo, Sao Paulo, Brazil.
⁴ Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, Syracuse.

Abstract

This mendelian randomization analyzes the potential causality between physical activity and schizophrenia.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Body Mass Index
Exercise / statistics & numerical data*
Female
Genome-Wide Association Study*
Humans
Male
Mendelian Randomization Analysis*
Middle Aged
Risk
Schizophrenia / epidemiology*
Schizophrenia / genetics*