Moderate differentiation is a risk factor for extensive subclinical spread of cutaneous squamous cell carcinoma

Anna Eversman; Elisabeth H Tracey; Daniel Michalik; Marla Rodriguez; Vamsi Varra; Isaac N Briskin; Allison T Vidimos; Christine M Poblete-Lopez

doi:10.1016/j.jaad.2020.12.004

Moderate differentiation is a risk factor for extensive subclinical spread of cutaneous squamous cell carcinoma

J Am Acad Dermatol. 2021 Dec;85(6):1606-1608. doi: 10.1016/j.jaad.2020.12.004. Epub 2020 Dec 5.

Authors

Anna Eversman¹, Elisabeth H Tracey², Daniel Michalik², Marla Rodriguez¹, Vamsi Varra¹, Isaac N Briskin³, Allison T Vidimos², Christine M Poblete-Lopez⁴

Affiliations

¹ School of Medicine, Case Western Reserve University, Cleveland, Ohio.
² Department of Dermatology, Cleveland Clinic, Cleveland, Ohio.
³ Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio.
⁴ Department of Dermatology, Cleveland Clinic, Cleveland, Ohio. Electronic address: lopezc@ccf.org.

PMID: 33290800
DOI: 10.1016/j.jaad.2020.12.004

No abstract available

Keywords: AUC; MMS; Mohs micrographic surgery; NCCN guidelines; aggressive SCC; appropriate use criteria; cutaneous oncology; dermatologic surgery; moderate differentiation; tumor grade.

Publication types

Letter

MeSH terms

Aged
Aged, 80 and over
Carcinoma, Squamous Cell* / epidemiology
Carcinoma, Squamous Cell* / surgery
Cell Differentiation
Female
Humans
Male
Middle Aged
Mohs Surgery
Neoplasm Recurrence, Local / surgery
Retrospective Studies
Risk Factors
Skin Neoplasms* / epidemiology
Skin Neoplasms* / surgery