Biosafety during a pandemic: shared resource laboratories rise to the challenge

Cytometry A. 2021 Jan;99(1):68-80. doi: 10.1002/cyto.a.24280. Epub 2021 Jan 4.

Abstract

Biosafety has always been an important aspect of daily work in any research institution, particularly for cytometry Shared Resources Laboratories (SRLs). SRLs are common-use spaces that facilitate the sharing of knowledge, expertise, and ideas. This sharing inescapably involves contact and interaction of all those within this working environment on a daily basis. The current pandemic caused by SARS-CoV-2 has prompted the re-evaluation of many policies governing the operations of SRLs. Here we identify and review the unique challenges SRLs face in maintaining biosafety standards, highlighting the potential risks associated with not only cytometry instrumentation and samples, but also the people working with them. We propose possible solutions to safety issues raised by the COVID-19 pandemic and provide tools for facilities to adapt to evolving guidelines and future challenges.

Keywords: COVID-19; SARS-CoV-2; biosafety guidelines; cytometry; emerging disease; epidemic; flow cytometry; pandemic; shared resource laboratory (SRL).

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control
  • COVID-19 / transmission
  • Containment of Biohazards / standards
  • Containment of Biohazards / trends*
  • Flow Cytometry
  • Humans
  • Laboratories / standards
  • Laboratories / trends*
  • Risk Assessment / standards
  • Risk Assessment / trends