Socio-ecological and pharmacy-level factors associated with naloxone stocking at standing-order naloxone pharmacies in New York City

Drug Alcohol Depend. 2021 Jan 1:218:108388. doi: 10.1016/j.drugalcdep.2020.108388. Epub 2020 Oct 24.

Abstract

Background: Research on socio-ecological factors that may impede or facilitate access to naloxone in pharmacies remains limited. This study investigated associations between socio-ecological factors, pharmacy participation in the naloxone cost assistance program (NCAP), pharmacy characteristics and having naloxone in stock among pharmacies in New York City.

Methods: Phone interviews were conducted with 662 pharmacies selected from the New York City Naloxone Standing Order List. Multi-level generalized linear modeling estimated associations between neighborhood racial and ethnic composition, poverty rates, overdose fatality rates, pharmacy participation in N-CAP, having private physical spaces within the pharmacy, knowledge of where to refer people to obtain naloxone and adjusted relative risk (aRR) that the pharmacy would have naloxone in stock.

Results: Findings from this study supported several of the hypotheses. Greater neighborhood poverty was associated with a lower likelihood of carrying naloxone compared to neighborhoods with less poverty (aRR = .79, CI95 % = .69, .90, p < .001). Pharmacies that provided a private window for consultations (aRR = 1.34, CI95 % = 1.19, 1.51, p < .001), a private room (aRR = 1.42, CI95 % = 1.30, 1.56, p < .001), and a private area (aRR = 1.42, CI95 % = 1.30, 1.56, p < .001) were associated with a higher likelihood of carrying naloxone compared than those that did not.

Conclusions: Findings from this study suggest that community-level socioeconomic marginalization is a contributor to disparities in naloxone availability among pharmacies in New York City. Findings support harm reduction interventions tailored to the built environment of pharmacies that respect privacy to those seeking naloxone.

Keywords: Harm reduction; Naloxone; Neighborhoods; Overdose; Pharmacy; Socioeconomic disparity.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Drug Overdose
  • Ethnicity
  • Female
  • Harm Reduction
  • Humans
  • Male
  • Naloxone / economics*
  • New York City
  • Pharmaceutical Services*
  • Pharmacies / economics*
  • Pharmacy
  • Racial Groups
  • Residence Characteristics
  • Standing Orders
  • Surveys and Questionnaires

Substances

  • Naloxone