[Reaserch Advances in Immunotherapy for Acute Myeloid Leukemia--Review]

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020 Dec;28(6):2089-2092. doi: 10.19746/j.cnki.issn.1009-2137.2020.06.048.
[Article in Chinese]

Abstract

Acute myeloid leukemia (AML) is a malignant tumor with abnormal myelocyte differentiation. With the development of immunological technology, great importance has been attached to the immunotherapy of AML patients, which may become an effective treatment strategy for AML, and providing a new means for the prognosis and survival. In this review, the advanced research of immunotherapy for AML, such as antibody-dependent drugs, chimeric antigen receptor T cell therapy, and checkpoint inhibitors, the bastest reaserch advanves of clinical experiment for immunotherapy was summarized briefly.

题目: 急性髓系白血病免疫治疗药物的研究进展.

摘要: 急性髓系白血病 (AML)是一种髓系细胞分化异常的恶性肿瘤。随着肿瘤免疫研究的不断深入, 免疫治疗在AML患者中的作用日益受到重视, 免疫治疗可能成为AML的有效治疗方案, 为该病的预后与生存提供新的武器。本文总结目前AML免疫治疗的主要方法如抗体依赖药物、嵌合型抗原受体T细胞疗法、免疫检测点抑制剂等, 对免疫治疗药物及临床试验最新研究进展作一综述.

Publication types

  • Review

MeSH terms

  • Humans
  • Immunologic Factors
  • Immunotherapy
  • Immunotherapy, Adoptive
  • Leukemia, Myeloid, Acute* / therapy
  • T-Lymphocytes*

Substances

  • Immunologic Factors