Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion

Bengi Ece Kurtul; Ayșe İdil Çakmak; Ahmet Elbeyli; Deniz Özarslan Özcan; Sait Coșkun Özcan; Veysel Cankurtaran

doi:10.1177/2515841420971949

Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion

Ther Adv Ophthalmol. 2020 Nov 18:12:2515841420971949. doi: 10.1177/2515841420971949. eCollection 2020 Jan-Dec.

Authors

Bengi Ece Kurtul¹, Ayșe İdil Çakmak², Ahmet Elbeyli², Deniz Özarslan Özcan², Sait Coșkun Özcan², Veysel Cankurtaran²

Affiliations

¹ Department of Ophthalmology, Tayfur Ata Sökmen Faculty of Medicine, Hatay Mustafa Kemal University, 31060, Alahan, Hatay, Turkey.
² Department of Ophthalmology, Tayfur Ata Sökmen Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, Turkey.

Abstract

Purpose: To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients.

Methods: In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count.

Results: Age and gender were comparable between the groups (p = 0.204 and p = 0.800, respectively). PLR was significantly elevated in the RVO group compared with the control group (137 (113-164) vs 101 (86-129), p = 0.001)). In the receiver operator characteristics curve analysis, the optimal cut-off value of PLR for predicting RVO was 123, with 69% sensitivity and 72% specificity.

Conclusion: We report that PLR are elevated in RVO, suggesting that PLR may be a useful marker for RVO.

Keywords: inflammation; platelet-to-lymphocyte ratio; retinal vein occlusion; thrombus.