Traumatic brain injury probability of survival assessment in adults using iterative random comparison classification

Healthc Technol Lett. 2020 Nov 18;7(5):119-124. doi: 10.1049/htl.2019.0029. eCollection 2020 Oct.

Abstract

Trauma brain injury (TBI) is the most common cause of death and disability in young adults. A method to determine the probability of survival (Ps) in trauma called iterative random comparison classification (IRCC) was developed and its performance was evaluated in TBI. IRCC operates by iteratively comparing the test case with randomly chosen subgroups of cases from a database of known outcomes (survivors and not survivors) and determines the overall percentage match. The performance of IRCC to determine Ps in TBI was compared with two existing methods. One was Ps14 that uses regression and the other was predictive statistical diagnosis (PSD) that is based on Bayesian statistic. The TBI database contained 4124 adult cases (mean age 67.9 years, standard deviation 21.6) of which 3553 (86.2%) were survivors and 571 (13.8%) were not survivors. IRCC determined Ps for the survivors and not survivors with an accuracy of 79.0 and 71.4%, respectively, while the corresponding values for Ps14 were 97.4% (survivors) and 40.2% (not survivors) and for PSD were 90.8% (survivors) and 50% (not survivors). IRCC could be valuable for determining Ps in TBI and with a suitable database in other traumas.

Keywords: Bayes methods; IRCC; Ps14; TBI database; adult cases; biomechanics; brain; computerised tomography; diseases; injuries; iterative methods; iterative random comparison classification; medical image processing; neurophysiology; paediatrics; regression analysis; statistical analysis; survival assessment; survivors; trauma brain injury; traumatic brain injury probability; young adults.