Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

Matevz Skerget; Tadej Dovsak; Gregor Kos; Samo Zver

doi:10.4081/hr.2020.8396

Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

Hematol Rep. 2020 Nov 17;12(2):8396. doi: 10.4081/hr.2020.8396. eCollection 2020 Nov 16.

Authors

Matevz Skerget^{1

2}, Tadej Dovsak^{1

2}, Gregor Kos³, Samo Zver^{1

2}

Affiliations

¹ University Medical Centre Ljubljana.
² Faculty of Medicine, University of Ljubljana.
³ Institute of Oncology Ljubljana, Slovenia.

Abstract

Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10-30%. In our case-cohort, thorough, sensitive initial evaluation for disseminated clonal disease and the incorporation of surgery led to excellent results with no recurrences or systemic progression.

Keywords: Extramedullary plasmacytoma; head and neck; radiotherapy; surgery.