1 Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg 79104, Germany. Electronic address: cube@imbi.uni-freiburg.de.
2 Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg 79104, Germany.
3 Infections Antimicrobials Modelling Evolution, UMR 1137, INSERM, Université Paris Diderot, Paris, France; Medical and Infectious Diseases Intensive Care Unit, Assistance Publique-Hôpitaux de Paris, Bichat Hospital, Paris, France.