[Nutritional Management in Cancer Chemotherapy Based on Pathophysiology of Sarcopenia]

Gan To Kagaku Ryoho. 2020 Nov;47(11):1552-1556.
[Article in Japanese]

Abstract

There are 4 purposes in the nutritional management for cancer patient. At first, we had better perform the early metabolic recovery from several invasive damages by some cancer treatments. At second, we give some special nutritional management for improvement from cancer cachexia. At third, we consider palliative nutritional management to terminal cancer patients based on pathophysiology of cachexia, their life styles and ethics. Finally, we give the social nutritional management for keeping high quality of life through well eating until the end of life. The basic nutritional management for cancer patients is administration of adequate amount of energy, protein/amino acids and micronutrients with suitable rehabilitation in order to prevent sarcopenia and malnutrition. In this paper, we explained about the metabolic influences to normal tissues, especially skeletal muscle, during chemotherapy. Also we mentioned importance to prevent sarcopenia and malnutrition during cancer treatment especially chemotherapy. Additionally, we showed the new topic about assessment for malnutrition, such as GLIM criteria, which is the global nutritional assessment formula for malnutrition including weight loss, low BMI and reduce of muscle mass. Now, we can recommend to use the global nutritional assessment and nutritional therapies even for cancer patients.

MeSH terms

  • Cachexia / etiology
  • Cachexia / therapy
  • Humans
  • Malnutrition* / etiology
  • Malnutrition* / therapy
  • Neoplasms* / complications
  • Neoplasms* / drug therapy
  • Nutrition Assessment
  • Nutritional Status
  • Quality of Life
  • Sarcopenia* / etiology
  • Sarcopenia* / therapy