Depression has a high incidence in patients with cardiovascular diseases (CVD) and shows adverse effects on their life quality and prognosis. With the advent of new antidepressant drugs, oral antidepressant drugs are increasingly used in CVD patients with depression, and their efficacy and safety have attracted attention. Commonly used antidepressant drugs have many adverse reactions. When applying antidepressant drugs in CVD patients, we should pay special attention to their cardiovascular adverse reactions and their interaction drugs with commonly used CVD drugs. Clinicians should comprehensively evaluate and select appropriate antidepressant drugs for patients.
在心血管疾病(cardiovascular diseases，CVD)患者中抑郁有较高的发病率，抑郁对心血管疾病患者的生活质量和预后有不利的影响。随着新型抗抑郁药的问世，口服抗抑郁药在CVD合并抑郁患者中的应用越来越多，其疗效及安全性是人们关注的热点。常用抗抑郁药均有许多不良反应。在CVD患者中应用抗抑郁药时，尤其应重视其心血管方面的不良反应及与CVD常用药物间的相互作用。临床医生在选择药物时应综合评估，并为患者选择合适的抗抑郁药。.
Keywords: adverse reactions; antidepressant drugs; cardiovascular diseases; depression; safety.