Surgical site complications of post-chemoradiotherapy neck dissection: Urgent need for standard registration

Roel Henneman; Winnie Schats; M Baris Karakullukcu; Michiel Wm van den Brekel; Ludwig E Smeele; Peter Fjm Lohuis; Jos A van der Hage; Abrahim Al-Mamgani; Alfons Jm Balm

doi:10.1016/j.ejso.2020.10.015

Surgical site complications of post-chemoradiotherapy neck dissection: Urgent need for standard registration

Eur J Surg Oncol. 2021 Apr;47(4):764-771. doi: 10.1016/j.ejso.2020.10.015. Epub 2020 Oct 15.

Authors

Roel Henneman¹, Winnie Schats², M Baris Karakullukcu³, Michiel Wm van den Brekel⁴, Ludwig E Smeele³, Peter Fjm Lohuis³, Jos A van der Hage⁵, Abrahim Al-Mamgani⁶, Alfons Jm Balm³

Affiliations

¹ Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands. Electronic address: r.henneman@nki.nl.
² Scientific Information Service, Netherlands Cancer Institute, Amsterdam, the Netherlands.
³ Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands; Department of Oral and Maxillofacial Surgery, Amsterdam UMC, Amsterdam, the Netherlands.
⁴ Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands; Department of Oral and Maxillofacial Surgery, Amsterdam UMC, Amsterdam, the Netherlands; Institute of Phonetic Sciences-Amsterdam Center of Language and Communication, University of Amsterdam, the Netherlands.
⁵ Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
⁶ Department of Radiation Oncology, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

PMID: 33268211
DOI: 10.1016/j.ejso.2020.10.015

Abstract

Nowadays, a substantial number of head and neck cancer patients are treated by organ-preserving chemoradiation (CRT), with a possible increased risk of complications after planned or salvage neck dissections. We try to determine the risk pattern of surgical site complications (SSC) post-CRT.

Keywords: Chemoradiotherapy; Complication; Lymph node metastasis; Multimodality treatment; Neck dissection; Organ preservation therapy; Planned neck dissection; Salvage therapy; Surgical site infection; Systematic review.

Publication types

Systematic Review

MeSH terms

Chemoradiotherapy / adverse effects*
Head and Neck Neoplasms / therapy*
Humans
Neck Dissection / adverse effects*
Postoperative Complications / etiology*
Postoperative Hemorrhage / etiology
Surgical Wound Dehiscence / etiology
Surgical Wound Infection / etiology