A Potential Health Risk to Occupational User from Exposure to Biocidal Active Chemicals

Int J Environ Res Public Health. 2020 Nov 25;17(23):8770. doi: 10.3390/ijerph17238770.

Abstract

Biocidal active chemicals have potential health risks associated with exposure to retail biocide products such as disinfectants for COVID-19. Reliable exposure assessment was investigated to understand the exposure pattern of biocidal products used by occupational workers in their place of occupation, multi-use facilities, and general facilities. The interview-survey approach was taken to obtain the database about several subcategories of twelve occupational groups, the use pattern, and the exposure information of non-human hygiene disinfectant and insecticide products in workplaces. Furthermore, we investigated valuable exposure factors, e.g., the patterns of use, exposure routes, and quantifying potential hazardous chemical intake, on biocidal active ingredients. We focused on biocidal active-ingredient exposure from products used by twelve occupational worker groups. The 685 non-human hygiene disinfectants and 763 insecticides identified contained 152 and 97 different active-ingredient chemicals, respectively. The toxicity values and clinical health effects of total twelve ingredient chemicals were determined through a brief overview of toxicity studies aimed at estimating human health risks. To estimate actual exposure amounts divided by twelve occupational groups, the time spent to apply the products was investigated from the beginning to end of the product use. This study investigated the exposure assessment of occupational exposure to biocidal products used in workplaces, multi-use facilities, and general facilities. Furthermore, this study provides valuable information on occupational exposure that may be useful to conduct accurate exposure assessment and to manage products used for quarantine in general facilities.

Keywords: exposure assessment; hazardous ingredients; insecticide; non-human hygiene disinfectant; toxicological endpoint.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19
  • Disinfectants / adverse effects*
  • Humans
  • Insecticides / adverse effects*
  • Occupational Exposure*
  • Occupational Health*
  • Occupations
  • Pandemics
  • Risk Assessment

Substances

  • Disinfectants
  • Insecticides