Mesenteric Phlebosclerosis Associated with Herbal Medicine

Kimitoshi Kubo; Noriko Kimura; Norishige Maiya; Soichiro Matsuda; Momoko Tsuda; Mototsugu Kato

doi:10.1159/000508931

Mesenteric Phlebosclerosis Associated with Herbal Medicine

Case Rep Gastroenterol. 2020 Oct 27;14(3):516-521. doi: 10.1159/000508931. eCollection 2020 Sep-Dec.

Authors

Kimitoshi Kubo¹, Noriko Kimura², Norishige Maiya¹, Soichiro Matsuda¹, Momoko Tsuda¹, Mototsugu Kato¹

Affiliations

¹ Department of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, Japan.
² Department of Pathology, National Hospital Organization Hakodate National Hospital, Hakodate, Japan.

Abstract

Mesenteric phlebosclerosis (MP) associated with herbal medicine is rarely reported and its endoscopic and radiological features remain poorly described. An 81-year-old woman was admitted to our hospital for right lower abdominal pain and high-grade fever. Computed tomography (CT) revealed wall thickening, pericolic fat stranding, and linear calcifications extending from the cecum to the hepatic flexure of the colon. Ultrasonography (US) revealed wall thickening of the cecum and ascending colon. Colonoscopy (CS) revealed dark-purple edematous mucosa with erosion and ulcers from the cecum to the hepatic flexure of the colon. The patient was histopathologically diagnosed with MP, discontinued orengedokuto, and was treated with intravenous antibiotics for 1 week. Six months after treatment, US and CT revealed no significant changes, but CS showed improvement in dark-purple edematous mucosa with erosion and ulcers. To our knowledge, this report represents a valuable addition to the MP literature describing a rare case of MP associated with herbal medicine.

Keywords: Herbal medicine; Mesenteric phlebosclerosis; Mesenteric vein calcification.

Publication types

Case Reports