A rotating disk sorptive extraction based on hydrophilic deep eutectic solvent formation

Andrey Shishov; Natalia Volodina; Svetlana Gagarionova; Vladimir Shilovskikh; Andrey Bulatov

doi:10.1016/j.aca.2020.10.020

A rotating disk sorptive extraction based on hydrophilic deep eutectic solvent formation

Anal Chim Acta. 2021 Jan 2:1141:163-172. doi: 10.1016/j.aca.2020.10.020. Epub 2020 Oct 16.

Authors

Andrey Shishov¹, Natalia Volodina², Svetlana Gagarionova², Vladimir Shilovskikh³, Andrey Bulatov²

Affiliations

¹ Department of Analytical Chemistry, Institute of Chemistry, Saint-Petersburg University, Saint Petersburg State University, SPbSU, SPbU, 7/9 Universitetskaya nab., St. Petersburg, 199034, Russia. Electronic address: a.y.shishov@spbu.ru.
² Department of Analytical Chemistry, Institute of Chemistry, Saint-Petersburg University, Saint Petersburg State University, SPbSU, SPbU, 7/9 Universitetskaya nab., St. Petersburg, 199034, Russia.
³ Infochemistry Scientific Center of ITMO University, 9, Lomonosova str., St. Petersburg, 191002, Russia.

PMID: 33248649
DOI: 10.1016/j.aca.2020.10.020

Abstract

An elegant preconcentration method assumed sorption of polar analytes from complex non-polar matrices on a rotating disk based on hydrophilic deep eutectic solvent formation is presented for the first time. The surface of poly(vinylidene fluoride-co-tetrafluoroethylene) rotating disk was coated with choline chloride acted as a precursor of deep eutectic solvent (hydrogen bond acceptor). The rotating disk was immersed in vegetable oil sample and phenolic compounds (hydrogen bond donors) were efficient separated on the disk during its rotation due to deep eutectic solvent formation. Ability of hydrophilic deep eutectic solvent decomposition in aqueous phase was used for fast analytes elution from the disk surface (2 min). Finally, the obtained aqueous solution of phenolic compounds and choline chloride was analyzed by high-performance liquid chromatography with fluorescence detection. Under optimal conditions, the limits of detection for gallic acid, protocatechuic acid, tyrosol, vanillic acid, p-coumarinic acid, syringaldehyde and thymol were in the range of 10-60 μg L^-1. The developed approach allowed to significantly reduce sorption and elution time in comparison with previously reported rotating disk sorptive extraction approaches. The extraction mechanism based on deep eutectic solvent formation provided selective separation of target analytes with absolute extraction recovery in the range of 66-87%.

Keywords: Deep eutectic solvent; HPLC-FLD; Phenolic compounds; Rotating disk; Rotating disk sorptive extraction; Sorption; Vegetable oil.