Something Old, Something New: the ACR Gout Treatment Guideline and Its Evolution from 2012 to 2020

Curr Rheumatol Rep. 2020 Nov 27;23(1):4. doi: 10.1007/s11926-020-00967-8.

Abstract

Purpose of review: Gout is the most common inflammatory arthritis in the USA, affecting about 4% of all adults. The American College of Rheumatology (ACR) released a new guideline in 2020 to help with the management of gout. This guideline serves as an update to the previous set of guidelines which the ACR published in 2012. The purpose of this review is to compare the 2012 ACR gout guidelines to the newly released 2020 ACR gout guidelines.

Recent findings: There are many similarities between the two guidelines, and also several key differences. The 2020 guidelines assist in the clinical management of gout by healthcare providers. Additionally, the new guidelines utilize newer literature to help create an evidence-based approach to the treatment for gout. We discuss the methodological approach to each guideline (RAND versus GRADE), as well as the final recommendations for gout flare treatment, use of imaging, urate-lowering therapy, lifestyle changes, and genetic testing prior to initiation of allopurinol in each guideline, as well as lingering issues that the 2020 guidelines have not addressed. We dissect both the 2012 and 2020 ACR gout guidelines to summarize the key similarities and differences between the two as well as discuss how the authors came to the recommendations that they did for each set of guidelines.

Keywords: Allopurinol; Colchicine; Febuxostat; Gout; Guidelines.

Publication types

  • Review

MeSH terms

  • Allopurinol / therapeutic use
  • Gout Suppressants / therapeutic use
  • Gout* / diagnosis
  • Gout* / drug therapy
  • Humans
  • Practice Guidelines as Topic*
  • Rheumatology*
  • Symptom Flare Up
  • United States

Substances

  • Gout Suppressants
  • Allopurinol