Caring for Hospitalized Patients with Diabetes Mellitus, Hyperglycemia, and COVID-19: Bridging the Remaining Knowledge Gaps

Curr Diab Rep. 2020 Nov 26;20(12):77. doi: 10.1007/s11892-020-01366-0.

Abstract

Purpose of review: This review discusses the interplay between coronavirus disease 2019 (COVID-19, caused by SARS-CoV-2 infection), diabetes mellitus, and hyperglycemia in the hospital setting. There are data emerging about diabetes and hyperglycemia, their prevalence, and potential risks in the setting of SARS-CoV-2 infection and COVID-19.

Recent findings: It is known that viral infections exert effects on beta cell function and insulin resistance. Therefore, much can be learned about SARS-CoV-2/COVID-19 from examining these known relationships. Such pathophysiological underpinnings may unlock greater understanding as we navigate atypical cases of hyperglycemia, severe insulin resistance, and diabetic ketoacidosis amidst COVID-19. Glycemic outcomes likely have beneficial effects on morbidity and mortality, but this needs to be studied. Changes in diabetes-related protocols and new technology can be deployed in the inpatient setting to potentially improve healthcare worker and patient safety; however, one must weigh the risks and benefits of implementation during a pandemic. Ultimately, knowledge and research must be shared at record speed to combat this global crisis.

Keywords: Covid-19; Diabetes; Hyperglycemia; Inpatient management; SARS-CoV2.

Publication types

  • Review

MeSH terms

  • Betacoronavirus*
  • COVID-19*
  • Coronavirus Infections* / epidemiology
  • Diabetes Mellitus* / epidemiology
  • Humans
  • Hyperglycemia*
  • Pandemics
  • Pneumonia, Viral* / epidemiology
  • SARS-CoV-2