Epidemiology of Thyroid Cancer: Incidence and Mortality in China, 2015

Lingbin Du; Zixuan Zhao; Rongshou Zheng; Huizhang Li; Siwei Zhang; Runhua Li; Wenqiang Wei; Jie He

doi:10.3389/fonc.2020.01702

Epidemiology of Thyroid Cancer: Incidence and Mortality in China, 2015

Front Oncol. 2020 Nov 10:10:1702. doi: 10.3389/fonc.2020.01702. eCollection 2020.

Authors

Lingbin Du¹, Zixuan Zhao², Rongshou Zheng³, Huizhang Li¹, Siwei Zhang³, Runhua Li⁴, Wenqiang Wei³, Jie He⁵

Affiliations

¹ Department of Cancer Prevention, Institute of Cancer and Basic Medicine, Zhejiang Cancer Hospital, Chinese Academy of Sciences, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, China.
² Center for Health Policy Studies, School of Medicine, Zhejiang University, Hangzhou, China.
³ Office for Cancer Registry, National Cancer Center, National Clinical Research Center for Cancer, Peking Union Medical College, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.
⁴ Department of Prevention & Health Care, Institute of Cancer and Basic Medicine, Zhejiang Cancer Hospital, Chinese Academy of Sciences, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, China.
⁵ Department of Thoracic Surgery, National Cancer Center, National Clinical Research Center for Cancer, Peking Union Medical College, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Abstract

Objective: Using data from cancer registries to estimate thyroid cancer incidence and mortality in China, 2015. Methods: Data submitted from local cancer registries were checked and evaluated according to the criteria of data quality control, a total of 368 cancer registries' data were qualified for the final analysis. Data were stratified by area (urban/rural, eastern/central/western), sex and age, combined with national population data to estimate thyroid cancer incidence and mortality in China, 2015. Results: Approximately 200,700 new cases were diagnosed in 2015, accounting for 5.11% of all cancer cases. The crude incidence rate was 14.60/100,000. Age-standardized incidence rates by Chinese standard population (ASIRC) and world standard population (ASIRW) were 12.05/100,000 and 10.44/100,000, with the cumulative incidence rate (0-74 years old) of 1.00%. About 7,900 deaths of thyroid cancer were reported in 2015, accounting for 0.34% of all cancer deaths. The crude mortality rate was 0.58/100,000, age-standardized mortality rates by Chinese standard population (ASMRC) and world standard population (ASMRW) were 0.37/100,000 and 0.36/100,000. The age-standardized incidence and mortality in females were significantly higher than those in males (P < 0.001). The rates in urban areas were higher than those in rural areas (P < 0.001). The ASIRC in eastern areas was higher than that in central and western areas (P < 0.001), while the ASMRC in central areas was higher than that in eastern and western areas (P < 0.001). Conclusions: The burden of thyroid cancer was heavy in China, cancer control faces the problem of the disparity between geographic areas, and the incidence and mortality rates were varied by sex and age. Targeted cancer preventive measures should be put into practice.

Keywords: China; cancer registry; incidence; mortality; thyroid cancer.