Carrageenan: Drug Delivery Systems and Other Biomedical Applications

Mar Drugs. 2020 Nov 23;18(11):583. doi: 10.3390/md18110583.

Abstract

Marine resources are today a renewable source of various compounds, such as polysaccharides, that are used in the pharmaceutical, medical, cosmetic, and food fields. In recent years, considerable attention has been focused on carrageenan-based biomaterials due to their multifunctional qualities, including biodegradability, biocompatibility, and non-toxicity, in addition to bioactive attributes, such as their antiviral, antibacterial, antihyperlipidemic, anticoagulant, antioxidant, antitumor, and immunomodulating properties. They have been applied in pharmaceutical formulations as both their bioactive and physicochemical properties make them suitable biomaterials for drug delivery, and recently for the development of tissue engineering. This article provides a review of recent research on the various types of carrageenan-based biomedical and pharmaceutical applications.

Keywords: biological activity; carrageenan; drug delivery; marine polysaccharide.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Carrageenan / chemistry*
  • Carrageenan / pharmacology*
  • Drug Carriers*
  • Drug Compounding
  • Hematologic Agents / chemistry
  • Hematologic Agents / pharmacology
  • Humans
  • Hypolipidemic Agents / chemistry
  • Hypolipidemic Agents / pharmacology
  • Immunologic Factors / chemistry
  • Immunologic Factors / pharmacology
  • Molecular Structure
  • Structure-Activity Relationship

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents
  • Antioxidants
  • Drug Carriers
  • Hematologic Agents
  • Hypolipidemic Agents
  • Immunologic Factors
  • Carrageenan