RETRACTED: LncRNA GAS6-AS1 facilitates the progression of breast cancer by targeting the miR-324-3p/SETD1A axis to activate the PI3K/AKT pathway

Sijie Li; Hongyao Jia; Zhiru Zhang; Di Wu

doi:10.1016/j.ejcb.2020.151124

RETRACTED: LncRNA GAS6-AS1 facilitates the progression of breast cancer by targeting the miR-324-3p/SETD1A axis to activate the PI3K/AKT pathway

Eur J Cell Biol. 2020 Nov;99(8):151124. doi: 10.1016/j.ejcb.2020.151124. Epub 2020 Sep 16.

Authors

Sijie Li¹, Hongyao Jia², Zhiru Zhang², Di Wu³

Affiliations

¹ Department of Breast Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. Electronic address: lisij@jlu.edu.cn.
² Department of Breast Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, China.
³ Department of Breast Surgery, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. Electronic address: wu_di@jlu.edu.cn.

PMID: 33223203
DOI: 10.1016/j.ejcb.2020.151124

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the current Editor in Chief, with the agreement of all authors. The article is being retracted due to inappropriate manipulation of the original data for presentation in Figures 2C, 5C and 6C. Upon further investigation and discussion with the authors, insufficient evidence was provided to support a reasonable explanation for these mistakes. In addition, the authors could not provide convincing original data supporting other figures of the manuscript, e.g. Figures 2G, 4 and 6A. Based on these findings, the Editor in Chief and the authors have decided to retract the study. The authors apologize for any inconvenience caused.

Keywords: Breast cancer; GAS6-AS1; PI3K/AKT pathway; SETD1A; miR-324-3p.

Publication types

Retracted Publication

MeSH terms

Disease Progression
Female
Humans
MicroRNAs / metabolism*
Phosphatidylinositol 3-Kinases / metabolism*
Proto-Oncogene Proteins c-akt / metabolism*
RNA, Long Noncoding / genetics*
Transfection
Up-Regulation

Substances

MIRN324 microRNA, human
MicroRNAs
RNA, Long Noncoding
Proto-Oncogene Proteins c-akt