Peripartum Cardiomyopathy

Cardiol Clin. 2021 Feb;39(1):119-142. doi: 10.1016/j.ccl.2020.09.008.

Abstract

Peripartum cardiomyopathy (PPCM) is a form of heart failure that occurs toward the end of pregnancy or in the months following pregnancy and is marked by left ventricular systolic dysfunction. The cause of PPCM remains unknown and there is no diagnostic test specific to PPCM. Outcomes vary and include complete left ventricular recovery, persistent cardiac dysfunction, transplant, and death. Numerous advances have been made in understanding this disease, but many knowledge gaps remain. This article reviews recent data and recommendations for clinical practice in addition to highlighting the multiple knowledge gaps related to PPCM that warrant further investigation.

Keywords: Heart failure; PPCM; Peripartum cardiomyopathy; Postpartum cardiomyopathy; Pregnancy.

Publication types

  • Review

MeSH terms

  • Cardiomyopathies* / diagnosis
  • Cardiomyopathies* / etiology
  • Cardiomyopathies* / physiopathology
  • Cardiomyopathies* / therapy
  • Female
  • Humans
  • Patient Care / methods*
  • Pregnancy
  • Pregnancy Complications, Cardiovascular* / diagnosis
  • Pregnancy Complications, Cardiovascular* / physiopathology
  • Pregnancy Complications, Cardiovascular* / therapy
  • Prognosis
  • Puerperal Disorders* / diagnosis
  • Puerperal Disorders* / physiopathology
  • Puerperal Disorders* / therapy
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / etiology