The Most Useful Pharmaceutical Formulations (Individualized Medications) in Pediatric Dermatology: A Review

Actas Dermosifiliogr (Engl Ed). 2021 Apr;112(4):302-313. doi: 10.1016/j.ad.2020.11.006. Epub 2020 Nov 18.
[Article in English, Spanish]

Abstract

The administration of appropriate doses of active ingredients and excipients is crucial for achieving desired treatment outcomes in pediatric dermatology. A number of factors need to be considered, including the characteristics of the lesion, the patient, and the drug. An additional challenge in pediatric settings is the limited number of commercially available formulations suitable for use in children. Drug compounding, which is the preparation of medications tailored to the needs of individual patients, is a good alternative for pediatric populations for a number of reasons. Using a customized compound, the clinician can prescribe formulations that contain the optimal dose of the active ingredients within acceptable limits and the most suitable vehicle and formulation components. Compounding can also be used to combine several active ingredients in a single medication and even adapt the vehicle to the characteristics of the lesion and the needs of the patient. The pharmaceutical formulations described in this review are based on extensive clinical experience and can be customized to meet individual needs.

Keywords: Active ingredients; Dermatology; Dermatología; Drug compounding; Formulación magistral; Medicamentos individualizados; Pediatrics; Pediatría; Pharmaceutical formulation; Principio activo; Vehicles; Vehículo.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological
  • Child
  • Dermatology*
  • Drug Compounding
  • Excipients
  • Humans
  • Pharmaceutical Preparations*

Substances

  • Excipients
  • Pharmaceutical Preparations