Spatial inequalities of COVID-19 mortality rate in relation to socioeconomic and environmental factors across England

Sci Total Environ. 2021 Mar 1:758:143595. doi: 10.1016/j.scitotenv.2020.143595. Epub 2020 Nov 13.

Abstract

In this study, we aimed to examine spatial inequalities of COVID-19 mortality rate in relation to spatial inequalities of socioeconomic and environmental factors across England. Specifically, we first explored spatial patterns of COVID-19 mortality rate in comparison to non-COVID-19 mortality rate. Subsequently, we established models to investigate contributions of socioeconomic and environmental factors to spatial variations of COVID-19 mortality rate across England (N = 317). Two newly developed specifications of spatial regression models were established successfully to estimate COVID-19 mortality rate (R2 = 0.49 and R2 = 0.793). The level of spatial inequalities of COVID-19 mortality is higher than that of non-COVID-19 mortality in England. Although global spatial association of COVID-19 mortality and non-COVID-19 mortality is positive, local spatial association of COVID-19 mortality and non-COVID-19 mortality is negative in some areas. Expectedly, hospital accessibility is negatively related to COVID-19 mortality rate. Percent of Asians, percent of Blacks, and unemployment rate are positively related to COVID-19 mortality rate. More importantly, relative humidity is negatively related to COVID-19 mortality rate. Moreover, among the spatial models estimated, the 'random effects specification of eigenvector spatial filtering model' outperforms the 'matrix exponential spatial specification of spatial autoregressive model'.

Keywords: COVID-19 mortality; Eigenvector spatial filtering model; Matrix exponential spatial specification model; Socioeconomic disadvantage; Spatial disparities.

MeSH terms

  • COVID-19*
  • England / epidemiology
  • Health Status Disparities
  • Humans
  • Mortality
  • SARS-CoV-2
  • Socioeconomic Factors