Acute chorioamnionitis complicated with symmetrical peripheral gangrene

Taiwan J Obstet Gynecol. 2020 Nov;59(6):972-974. doi: 10.1016/j.tjog.2020.09.032.

Abstract

Objective: Symmetrical peripheral gangrene (SPG) is an uncommon but important clinical syndrome. We present a case of acute chorioamnionitis complicated with SPG.

Case report: A 33-year-old female (gravida 5, para 2) was admitted with preterm premature rupture of membranes (PPROM) at 20 weeks and four days of gestation. She received cervical cerclage four days ago. Seven days after the diagnosis of PPROM, she developed fever, tachypnea and tachycardia. Termination of pregnancy was decided for clinical diagnosis of sepsis. After the abortus was born, gangrene change on the nose was noticed. Afterwards, this patient developed acrocyanosis of extremities. SPG developed following sepsis with intravascular disseminated coagulation (DIC). After intensive care, the patient underwent hyperbaric oxygen therapy and fasciectomy of the left forearm.

Conclusion: We suggest awareness of SPG associated with acute chorioamnionitis. Early recognition of SPG, multidisciplinary care, and treatment of its underlying conditions are the mainstays of management.

Keywords: Disseminated intravascular coagulation; Preterm premature rupture of membranes; Septic shock; Symmetrical peripheral gangrene.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Cerclage, Cervical
  • Chorioamnionitis / diagnosis*
  • Chorioamnionitis / etiology
  • Diagnosis, Differential
  • Disseminated Intravascular Coagulation / complications
  • Disseminated Intravascular Coagulation / diagnosis*
  • Female
  • Fetal Membranes, Premature Rupture / diagnosis*
  • Fetal Membranes, Premature Rupture / etiology
  • Foot / blood supply
  • Gangrene / complications
  • Gangrene / diagnosis*
  • Humans
  • Medical Illustration
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / diagnosis*
  • Pregnancy Complications, Cardiovascular / etiology
  • Upper Extremity / blood supply

Supplementary concepts

  • Preterm Premature Rupture of the Membranes