Acquisition and Transmission of Carbapenemase-Producing (blaKPC-2) Enterobacter cloacae in a Highly Frequented Outpatient Clinic

Sabrina Klein; Sébastien Boutin; Isabel Späth; Christoph Kimmich; Juliane Brandt; Carsten Müller-Tidow; Klaus Heeg; Dennis Nurjadi

doi:10.1093/cid/ciaa1734

Acquisition and Transmission of Carbapenemase-Producing (blaKPC-2) Enterobacter cloacae in a Highly Frequented Outpatient Clinic

Clin Infect Dis. 2021 Mar 1;72(5):e158-e161. doi: 10.1093/cid/ciaa1734.

Authors

Sabrina Klein¹, Sébastien Boutin¹, Isabel Späth¹, Christoph Kimmich², Juliane Brandt², Carsten Müller-Tidow², Klaus Heeg¹, Dennis Nurjadi¹

Affiliations

¹ Department of Infectious Diseases, Medical Microbiology and Hospital Hygiene, University Hospital Heidelberg, Heidelberg, Germany.
² Department of Hematology, Oncology, and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

PMID: 33211115
DOI: 10.1093/cid/ciaa1734

Abstract

The role of outpatient clinics as a potential transmission ground for multidrug-resistant organisms has not been adequately investigated. Here, we report a transmission cluster of blaKPC-2-positive Enterobacter cloacae among patients treated in a highly frequented outpatient department.

Keywords: Enterobacter cloacae; KPC-2 carbapenemase; outbreak; outpatient clinic; whole-genome sequencing.

MeSH terms

Ambulatory Care Facilities
Anti-Bacterial Agents / pharmacology
Bacterial Proteins / genetics
Enterobacter cloacae* / genetics
Enterobacteriaceae Infections* / epidemiology
Humans
Microbial Sensitivity Tests
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
Bacterial Proteins
beta-Lactamases
carbapenemase