Evolutionary study of COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as an emerging coronavirus: Phylogenetic analysis and literature review

Vet Med Sci. 2021 Mar;7(2):559-571. doi: 10.1002/vms3.394. Epub 2020 Nov 18.

Abstract

Since emerging coronaviruses have always become a human health concern globally especially severe acute respiratory syndrome coronavirus 2 (SARS-CoV) and Middle East respiratory syndrome coronavirus and a novel coronavirus was introduced in Wuhan, China, in December 2019 (called SARS-CoV-2), many researchers focused on its epidemics, virological and clinical features. SARS-CoV-2 is classified as Betacoronaviruses genus and Sarbecovirus subgenus (lineage B). The virus shows a great similarity with SARS-CoV and bat SARS-like coronaviruses. In this study, we evaluate SARS-CoV-2 virus phylogeny and evolution by using current virus and related sequences.

Keywords: COVID-19; evolutionary study; phylogenetic analysis; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Evolution*
  • COVID-19 / epidemiology
  • COVID-19 / virology*
  • Genome, Viral
  • Humans
  • Open Reading Frames
  • Phylogeny*
  • SARS-CoV-2 / classification*
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / pathogenicity
  • SARS-CoV-2 / physiology
  • Viral Zoonoses / epidemiology
  • Viral Zoonoses / virology*