The known unknowns of T cell immunity to COVID-19

Sci Immunol. 2020 Nov 18;5(53):eabe8063. doi: 10.1126/sciimmunol.abe8063.

Abstract

Tremendous progress has been made in understanding the role of T cell immunity in acute and convalescent COVID-19 infection. Here we shed light on the "known unknowns" of pre-existing and acquired T cell responses in relation to acute and convalescent SARS-CoV-2 infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / immunology*
  • COVID-19 / epidemiology
  • COVID-19 / immunology*
  • COVID-19 / virology
  • Host-Pathogen Interactions / immunology
  • Humans
  • Immunity, Cellular / immunology
  • Immunity, Humoral / immunology
  • Immunologic Memory / immunology*
  • Pandemics
  • SARS-CoV-2 / immunology*
  • SARS-CoV-2 / physiology
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / virology

Substances

  • Antibodies, Viral