Pneumocystis pneumonia, a COVID-19 mimic, reminds us of the importance of HIV testing in COVID-19

Clin Med (Lond). 2020 Nov;20(6):590-592. doi: 10.7861/clinmed.2020-0565.

Abstract

While clinical environments are highly focused on COVID-19, reports of missed or delayed treatment for conditions that imitate COVID-19, such as pneumonia caused by the fungus Pneumocystis jirovecii, are emerging. Given the uncertain spectrum of COVID-19 presentations and variable sensitivity of laboratory tests for SARS-CoV-2, there is a risk that, without a high index of suspicion, alternative aetiologies may be overlooked while pursuing a diagnosis of COVID-19. The British HIV Association has been calling for the inclusion of HIV testing in all patients admitted to hospital with suspected COVID-19. In this article we reflect on the importance of including HIV testing to prevent avoidable morbidity and mortality in our patients.

Keywords: COVID-19; HIV; PCP; Pneumocystis jirovecii; SARS-CoV-2.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections* / diagnosis
  • AIDS-Related Opportunistic Infections* / pathology
  • AIDS-Related Opportunistic Infections* / physiopathology
  • AIDS-Related Opportunistic Infections* / therapy
  • COVID-19
  • Coronavirus Infections
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Male
  • Middle Aged
  • Pandemics
  • Pneumocystis carinii
  • Pneumonia, Pneumocystis* / diagnosis
  • Pneumonia, Pneumocystis* / pathology
  • Pneumonia, Pneumocystis* / physiopathology
  • Pneumonia, Pneumocystis* / therapy
  • Pneumonia, Viral