Rapid and visual detection of Cd2+ based on aza-BODIPY near infrared dye and its application in real and biological samples for environmental contamination screening

Pornthip Piyanuch; Pramsak Patawanich; Jitnapa Sirirak; Kullatat Suwatpipat; Anyanee Kamkaew; Kevin Burgess; Nantanit Wanichacheva

doi:10.1016/j.jhazmat.2020.124487

Rapid and visual detection of Cd²⁺ based on aza-BODIPY near infrared dye and its application in real and biological samples for environmental contamination screening

J Hazard Mater. 2021 May 5:409:124487. doi: 10.1016/j.jhazmat.2020.124487. Epub 2020 Nov 5.

Authors

Pornthip Piyanuch¹, Pramsak Patawanich¹, Jitnapa Sirirak¹, Kullatat Suwatpipat¹, Anyanee Kamkaew², Kevin Burgess³, Nantanit Wanichacheva⁴

Affiliations

¹ Department of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom, 73000, Thailand.
² School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima, 30000, Thailand.
³ Department of Chemistry, Texas A & M University, Box 30012, College Station, TX 77842, USA.
⁴ Department of Chemistry, Faculty of Science, Silpakorn University, Nakhon Pathom, 73000, Thailand. Electronic address: wanichacheva_n@su.ac.th.

PMID: 33199148
DOI: 10.1016/j.jhazmat.2020.124487

Abstract

Cadmium highly toxic and hazardous, and it can adversely affect human health leading to serious disorders. Herein, a water-soluble near-infrared sensor based on aza-BODIPY (1) was developed for dual determination of Cd²⁺ in environmental and biological media. This sensor exhibited color change from colorless to green along with a fluorescence enhancement in the near-infrared (NIR) region via photoinduced electron transfer (PET) after complexation with Cd²⁺. Sensor 1 can be employed in aqueous media at physiological pH for quantitative monitoring. It shows rapid response with high sensitivity (detection limit of 2.8 ppb; linear correlation over [Cd²⁺] 1.33 - 6.67 µM) and selectivity over potentially interfering ions. NIR sensor 1 can be used to determine [Cd²⁺] in living cells and environmental samples.

Keywords: "Visual-eye" indicator; Biological sample; Cadmium sensor; Fluorescence sensor; Near infrared sensor.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Boron Compounds
Cadmium* / toxicity
Fluorescent Dyes*
Humans
Spectrometry, Fluorescence

Substances

Boron Compounds
Fluorescent Dyes
azaBDPBA compound
Cadmium