Adapted protocol of rate of force development and relaxation scaling factor for neuromuscular assessment in patients with knee osteoarthritis

Abstract

Background: The linear relationship between muscle torque and rate of torque rise/relaxation during rapid muscle contractions has been recently introduced as a novel measure of muscle quickness, termed rate of torque development/relaxation scaling factor (RTD-SF/RTR-SF). Because the standard assessment protocol includes potentially painful muscle contractions, the first purpose of this study was to validate an adapted RTD-SF/RTR-SF protocol for knee extensor muscles that utilizes lower submaximal intensities and can be used in knee osteoarthritis patients.

Methods: A cross-sectional study was performed on a group of healthy controls (n = 24) who underwent the standard RTD-SF/RTR-SF protocol (20-80% of maximum) and the knee osteoarthritis group (n = 24) who underwent the adapted protocol (20-60% of maximum). We calculated the RTD-SF, RTR-SF and the linearity (r²) for both relationships, based on both protocols in controls.

Results: The validity of the adapted protocol was acceptable (intraclass correlation coefficient = 0.77-0.93), with low within-participant variation (coefficient of variability <10%) for both outcome measures. Compared with the control group, the knee osteoarthritis group had similar RTD-SF, but lower linearity of RTD-SF (0.90 vs. 0.82). The RTR-SF (8.0/s vs. 6.7/s) and its linearity (0.87 vs. 0.73) were significantly reduced. Comparing the affected and the unaffected leg in the knee osteoarthritis group, the unaffected leg had greater maximal torque (96.2 vs. 84.1 Nm) and higher linearity for RTD-SF (0.86 vs. 0.80) and RTR-SF (0.82 vs. 0.73).

Conclusions: We confirmed the validity of the adapted RTD/RTR-SF protocol and its sensitivity to impairments associated with knee osteoarthritis.

Keywords: Knee; Osteoarthritis; Pain; Rate of torque development; Reduced intensity.