Identification of Proteins of Tobacco Mosaic Virus by Using a Method of Feature Extraction

Front Genet. 2020 Oct 9:11:569100. doi: 10.3389/fgene.2020.569100. eCollection 2020.

Abstract

Tobacco mosaic virus, TMV for short, is widely distributed in the global tobacco industry and has a significant impact on tobacco production. It can reduce the amount of tobacco grown by 50-70%. In this research of study, we aimed to identify tobacco mosaic virus proteins and healthy tobacco leaf proteins by using machine learning approaches. The experiment's results showed that the support vector machine algorithm achieved high accuracy in different feature extraction methods. And 188-dimensions feature extraction method improved the classification accuracy. In that the support vector machine algorithm and 188-dimensions feature extraction method were finally selected as the final experimental methods. In the 10-fold cross-validation processes, the SVM combined with 188-dimensions achieved 93.5% accuracy on the training set and 92.7% accuracy on the independent validation set. Besides, the evaluation index of the results of experiments indicate that the method developed by us is valid and robust.

Keywords: feature extraction; identification; machine learning; physicochemical properties; tobacco mosaic virus.