The Mystery of MIS-C Post-SARS-CoV-2 Infection

Trends Microbiol. 2020 Dec;28(12):956-958. doi: 10.1016/j.tim.2020.10.004. Epub 2020 Oct 14.

Abstract

Following emergence of the coronavirus disease 2019 (COVID-19) pandemic, a surge in the life-threatening illness now termed 'multisystem inflammatory syndrome in children' (MIS-C) has raised questions about the unique effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents. Two important new studies by Consiglio et al. and Gruber et al. have begun to shine light on the immune drivers of this enigmatic disease.

Publication types

  • Comment

MeSH terms

  • Adolescent
  • Betacoronavirus
  • COVID-19
  • Child
  • Coronavirus Infections* / epidemiology
  • Coronavirus*
  • Humans
  • Pandemics*
  • Pneumonia, Viral*
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome*
  • Systemic Inflammatory Response Syndrome

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related