Racial Variation in the Relationship of Glycemic Control with Fracture Risk in Elderly Patients with Diabetes

Diabetes Metab Syndr Obes. 2020 Nov 5:13:4153-4155. doi: 10.2147/DMSO.S272076. eCollection 2020.

Abstract

We investigated racial variation in glycemic control (glycated hemoglobin A1c [HbA1c]) with fracture risk in geriatric patients with diabetes. Compared to an HbA1c of 7.0-7.9% [53-63 mmol/mol], HbA1c ≥9.0% [≥75 mmol/mol] was associated with increased fracture risk among Blacks and those of Unknown race only. This increase was attenuated in Blacks after accounting for the relative frequency of patient-provider interaction.

Keywords: African Americans; diabetes; fragility fractures; glycemic control; racial differences.

Grants and funding

This study was supported in part by the West Virginia University grant CTSI grant U54GM104942 from the National Institutes of Health (NIH) and the Vanderbilt University CTSA grant UL1 TR00445 from NCATS/NIH.