Three new polyacetylenes from Atractylodes japonica Koidz.ez Kitam

Mengjue Rui; Guixin Chou

doi:10.1080/14786419.2020.1845673

Three new polyacetylenes from Atractylodes japonica Koidz.ez Kitam

Nat Prod Res. 2022 Apr;36(8):2063-2070. doi: 10.1080/14786419.2020.1845673. Epub 2020 Nov 12.

Authors

Mengjue Rui^{1

2}, Guixin Chou^{1

2}

Affiliations

¹ Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
² Shanghai R&D Centre for Standardization of Chinese Medicines, Shanghai, China.

PMID: 33176498
DOI: 10.1080/14786419.2020.1845673

Abstract

Three new polyacetylenes (1-3), together with six known polyacetylenes (4-9), were isolated from a 95% aqueous ethanol extract of the Atractylodes japonica Koidz.ez Kitam. Their structures were elucidated by HR-ESI -MS and NMR techniques as well as comparison with those reported in literatures. The cytotoxic activity of 1-3 were also evaluated.

Keywords: Atractylodes; Atractylodes japonica Koidz.ez Kitam; NMR; cytotoxicity; polyacetylenes.

MeSH terms

Atractylodes* / chemistry
Magnetic Resonance Spectroscopy
Polyacetylene Polymer
Polyynes / chemistry
Polyynes / pharmacology

Substances

Polyacetylene Polymer
Polyynes